Home > Genetics, High Blood Pressure, Hypertension > High Blood Pressure Traced Back to a Gene Variant

High Blood Pressure Traced Back to a Gene Variant

April 1st, 2009

HyperTensionIt must be with the genes. True enough high blood pressure may be traced back to a gene that serves as framework on how the kidney will process salt. The discovery will help in developing new approaches to treat the condition.

Researchers from the University of Maryland School of Medicine traced that people with the common variant of STK39 are prone to have higher blood pressure. Presence of that gene also predisposes one to a full blown hypertension.

The conclusion of the study was made after analyzing the genes of five groups of people from the United States and Europe. One fifth of the subject population had a copy or duplicates of the STK39.

The gene on spotlight is involved in the production of a protein which affects how the kidney processes salt in the human body. How this kidney processes go on play a vital role in one’s blood pressure.

The findings of the study may give way to the development of new drugs to treat hypertension and it may specifically target STK39. Knowing how the gene works may lead to personalized medicine and allow doctors to identify which drugs will be best for the patient.

Individuals with high blood pressure are prone to other strokes, cardiac failure, heart attacks, and kidney problems.

Aside from the gene factor, experts cite a lot of factors that are involved in hypertension. Some of these are obesity, a sedentary lifestyle, and smoking. Obesity is a major factor, and it’s so bad in so many ways. Obesity causes diabetes too — and to be honest, weight loss is NEEDED in the US for so many people, including myself.

The proponents of the study aim to help in determining which group of medicines will work best for specific groups of patients.

Genetics, High Blood Pressure, Hypertension

  1. No comments yet.
  1. No trackbacks yet.